CYTOPLASMIC OVEREXPRESSION OF CD95L IN ESOPHAGEAL ADENOCARCINOMA CELLS OVERCOMES RESISTANCE TO CD95-MEDIATED APOPTOSIS

Cytoplasmic Overexpression of CD95L in Esophageal Adenocarcinoma Cells Overcomes Resistance to CD95-Mediated Apoptosis

Introduction: The CD95/CD95L pathway plays a critical role in tissue homeostasis and immune system regulation; however, the function of this pathway in malignancy remains poorly understood.We hypothesized that CD95L expression in esophageal adenocarcinoma confers advantages Jeans to the neoplasm other than immune privilege.Methods: CD95L expression

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Investigation of Mechanical Characterization of Transversely Isotropic Rock Mass Based on Rigid Block Discrete Element Method

The laminated joints of transversely isotropic rock mass show strong discontinuity, inhomogeneity, anisotropy, and nonlinearity.This paper proposes a novel rigid block discrete element method (RB-DEM) to simulate the transversely isotropic rock mass.The balls in traditional DEM simulation are replaced by rigid blocks generated using FEM mesh.The co

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Radiometric Normalization of Temporal Images Combining Automatic Detection of Pseudo-Invariant Features from the Distance and Similarity Spectral Measures, Density Scatterplot Analysis, and Robust Regression

Radiometric precision is difficult to maintain in orbital images due to several factors (atmospheric conditions, Earth-sun distance, detector calibration, illumination, and viewing angles).These unwanted effects must be removed for radiometric consistency among temporal images, leaving only land-leaving radiances, for optimum change detection.A var

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